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Neurotechnology2023Impact: 1 out of 3, proof of concept

Speaking again after paralysis, thanks to a brain implant and AI

In Nature in 2023, researchers showed that a brain implant combined with deep learning allowed a person with paralysis to communicate at a median rate of 78 words per minute, with a median word error rate of 25%. It is a first demonstration in a single person taking part in a clinical trial, but it opens a serious path towards restoring fluent communication.

Nature, 2023Lire en français

Why is speech so hard to restore?

Severe paralysis can take away a person's arms and legs, but also their voice. The brain keeps preparing the words, yet the message no longer reaches the muscles of the mouth and throat. "Speech neuroprostheses" try to read that message directly from the brain and turn it into words.

Until now, these devices struggled to combine natural speed with expressiveness. Spelling out words letter by letter is slow and tiring. Natural conversation needs speed, a voice and a face that moves, not only a string of letters on a screen.

What did the researchers do?

The team worked with a person in a clinical trial who has severe paralysis of the limbs and voice. A very dense grid of electrodes, placed on the surface of the brain area that controls speech, records the activity of that area.

The person tries to say sentences silently. Deep-learning models (AI that learns from examples) are trained to link those brain signals to what they are trying to say. The system produces three outputs in real time: text, synthetic speech and the movements of a virtual face, an avatar.

For the voice, the team personalised it so that it sounds like the person's voice before their injury.

What do the results show?

For text, decoding reaches a median rate of 78 words per minute with a large vocabulary, and a median word error rate of 25%. In other words, in the typical case about one word in four is wrong, so the text is not yet perfect.

The synthesised speech is described as intelligible and fast. The avatar reproduces mouth and face movements, both for speaking and for communicative gestures that are not speech.

The models reached this performance with less than two weeks of training. That is short for a system that has to learn the link between brain signals and a large vocabulary.

Key figures

  • 78 words/minmedian rate of text decoding
  • 25%median word error rate
  • < 2 weeksof training were enough to reach this performance

What does this change for patients?

The aim is to restore fuller, "embodied" communication, with voice, face and the rhythm of a real conversation. For people locked inside their bodies, this could be a huge gain in independence, if the approach is confirmed.

Today it is a research demonstration. It is not a product available to patients.

What are the limits?

The study involves one person. We do not know whether results will be the same in others, with different brains and different causes of paralysis. The device requires brain surgery and heavy equipment.

A 25% error rate also means the text still needs checking. Larger, longer trials outside the laboratory are still needed to show how well it works.

Being understood when speaking is hard: Mima

This implant is research carried out with a single person, and it is not yet available to patients. It shows that people are working to give speech back to those paralysis has taken it from.

Mima does not replace this technology. But she can help you or a relative note what matters and prepare questions for the team, so your voice is well carried. One question: "Which communication aids already exist for me?"

Frequently asked questions

Can this implant read my thoughts?

No. The system decodes the words the person tries to say silently, from the activity of the brain's speech area. It does not read random thoughts.

How fast is it?

Text is decoded at a median rate of 78 words per minute, with a median word error rate of 25%, according to the study published in Nature in 2023.

Is this implant available to patients?

No. It is a research demonstration in a clinical trial with a single person. Larger studies are needed before any everyday use.

What is the avatar for?

The avatar is a virtual face that reproduces mouth and face movements for speech or communicative gestures, to make the exchange feel more natural.

The original study

Metzger SL, Littlejohn KT, Silva AB, et al. “A high-performance neuroprosthesis for speech decoding and avatar control.” Nature, 23 August 2023. DOI : 10.1038/s41586-023-06443-4

Read the full study in Nature

This article summarises a scientific study and is not medical advice.